Acapella

A Comprehensive Toolbox for High Content Analysis

Acapella® is a highly flexible and powerful image data processing system which can be applied to a broad range of applications. It comes with a set of ready made application solutions – known as “Scripts” – with instructions to use and modify, but it is also fully flexible for new algorithm development. The Acapella Script Collection is regularly extended and is available to all Acapella users.

Acapella is particularly suited to high throughput, high content cellular assays, especially multiplexed scenarios. Its open architecture allows the user to develop assays by building on essential analysis steps such as nucleus detection, cytoplasm detection, cell compartment detection and quantifying events within the detected segments, so that new assays are progressed from sure foundations. The user can select and combine algorithms by using visual feedback. A comprehensive range of best-fit algorithms is included, each optimized for cell type, staining and imaging condition.

Key Features

  • Set of ready made applications for immediate use, or to use as a starting point for new applications.
  • Open architecture for creation of new assays – provides ultimate flexibility for development of algorithms.
  • Optimized for high speed online image analysis and for processing large data sets.
  • Superior segmentation algorithms for accurate separation on even confluent cell layers.
  • Unique, comprehensive collection of algorithm sets for nucleus, cell body and spot detection - allows new applications to be developed by using “choose best-fit and combine” approach.
Acapella high content analysis

Acapella is also available in a Linux edition to offer full support for Unix based cluster technologies enabling ultra high speed image analysis and analysis of very large data sets.

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